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Additionally, the same researchers later treated 4-month-old AD model mice by gavage daily for 5 months, with 25 mg/kg SF, which significantly reduced Aβ plaque levels in the hippocampus and cerebral cortex, improved cognition, and was shown to reduce HDAC 1 and 3 levels, suggesting its potential to counteract Aβ-induced cytotoxicity in AD models [232]
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Results from a phase 3 study, published in the New England Journal of Medicine , showed that nearly all (99.9 percent) of participants taking lenacapavir were protected against HIV
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