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Ipamorelin is a GH secretagogue pentapeptide that selectively activates the GHS-R1a receptor (ghrelin receptor) without significantly stimulating the release of cortisol, prolactin, or ACTH

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A study highlighting the therapeutic potential of KOR ligands in MS employed the selective KOR agonist MR2034 (a benzomorphan derivative) in the EAE rat model, in which myelin basic protein (MBP) was used to induce demyelination [145]