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Mechanistically, augmented ischemia-reperfusion injury in the absence of GPx-1 may be caused by increased NFκB activation, as pyrrolidine dithiocarbamate (PDTC), an NFκB inhibitor, partially protects against neurotoxicity in this model (82)
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10.1016/j.stem.2023.02.008 75 LiW.LiK.WeiW.DingS
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