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By blocking NNMT, it stops nicotinamide being methylated to 1-methylnicotinamide and spares the SAM that reaction would spend
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Thereby, BPC 157 is easily applicable and safe without adverse effects (i.e., in ulcerative colitis trials) while toxicology studies showed that a lethal dose (LD1) can be not achieved (for review, see [1,2,3,4,5,6,7,8,9,10])
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