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Unlike the cells in 3D culture, cells growing in a 2D manner are attached to the ECM that they deposit on the culture dish surface [3]
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The pesticides alachlor atrazine and dichlorodiphenyltrichloroethane (DDT) are metabolized directly by GSTs by chloro-substitution reactions, which in the case of DDT is followed by spontaneous deglutathionylation leading to DDE (Figure 3b–d) [38,39]
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