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After completion of growth and development, the organism can maintain systemic copper homeostasis by controlling the balance between copper absorption and excretion ( Hence, the characteristic of copper metabolism in cancer cells may be their specific weakness compared to normal tissues ( 2 Physiological effects and metabolic processes of copper Copper plays an essential role in cellular metabolism, participating in many physiological processes such as the mitochondrial respiratory chain, antioxidant reactions, and biosynthesis of biomolecules

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