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Exp Gerontol (2005) 40(11):873–7.10.1016/j.exger.2005.06.014 254 ZhouYXuBCMaheshwariHGHeLReedMLozykowskiMet alA mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)
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The siRNA was stabilized by hydrogen bonding, electrostatic interaction, and hydrophobic interactions and showed improved circulation stability and delivery efficiency
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