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Creation of two ‘opposite-acting’ yeast-based assays for high throughput screening for ChaC1 inhibitors Since neither the in silico strategy nor the use of synthetic analogues could provide a tentative lead as an inhibitor against the ChaC1 enzyme, a random chemical compound library screening strategy was adopted
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Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
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