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In healthy adrenal tissue (N=15) ( Figure 2 ), we found strong nuclear LEF-1 expression in the subcapsular zone and the zona glomerulosa in line with the current model of centripetal cell renewal originating from the subcapsular area in the human adrenal cortex ( Figure 2 Next, we investigated the expression of CTNNB1 and LEF-1 as potential markers of Wnt/β-catenin signalling in ACC
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