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Other reported effects Beyond GI symptoms, clinical trials noted several other effects worth monitoring: Increased heart rate: A small, dose-dependent increase in resting heart rate was observed, consistent with what occurs with other GLP-1 agonists
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Notably, oral administration of multi-strain probiotic formulations has demonstrated significant improvements in anxiety and depressive symptoms in MS-exposed mice, suggesting that gut microbiota dysbiosis plays a pivotal role in the pathophysiology of MS-induced neuropsychiatric symptoms
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