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To conclude, selenium supplementation effectively counteracts metabolic disturbances integral to PCOS pathophysiology by reinforcing systemic antioxidant defenses and optimizing transcriptional regulation of glucose and lipid transporters

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The three primary scavenging enzymes involved in detoxifying the free radicals in mammalian systems are SOD, CAT and GPx.56 SOD dismutases the highly reactive superoxide anion to the less reactive species H2O2.57 CAT and GPx efficiently react with H2O2 to form water and molecular oxygen.58,59 GSH has a multifactorial role in antioxidant defence