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✔️ Mechanism of Action • Tirzepatide: Dual incretin (GIP + GLP-1) → enhanced metabolic impact • Wegovy: GLP-1 receptor agonist → now with higher receptor engagement ✔️ Weight Loss Outcomes • Tirzepatide: ~22% weight reduction in trials • Wegovy 7.2 mg: ~20–21% weight reduction 👉 The efficacy gap is narrowing significantly ✔️ Cardiometabolic Profile • Wegovy: Strong, established cardiovascular outcome data • Tirzepatide: Superior glycemic control and insulin sensitivity ✔️ Safety & Tolerability • Both therapies show dose-dependent GI side effects • Overall safety profiles remain comparable 💡 The Big Picture We are witnessing a shift from: ➡️ Single-hormone optimization (high-dose semaglutide) to ➡️ Multi-hormone targeting (tirzepatide) 📊 Conclusion While Wegovy is rapidly closing the efficacy gap with dose escalation, Tirzepatide continues to lead as a next-generation metabolic therapy
D3
Flow Rate:75 GPM
H.KumamotoC
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