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Um estudo retrospectivo em humanos mostrou que 7 de 12 pacientes com dor crônica no joelho apresentaram alívio por mais de 6 meses após uma única injeção de BPC 157. Um estudo piloto de 2025 com 2 adultos não demonstrou efeitos adversos sobre biomarcadores cardíacos, hepáticos, renais, tireoidianos ou de glicose após infusão intravenosa
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