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The GSH:GSSG ratio is used as the primary indicator of cellular redox status due to the GSH pool being approximately three to four orders of magnitude higher in abundance than other major redox couples, such as the pyridine nucleotide and related thiol couples [7,19]
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Three SOD isozymes are expressed in human cells, a cytosolic (SOD-1), a mitochondrial (SOD-2), and an extracellular (SOD-3) isoform
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