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mLST8 is associated with the catalytic domain of mTOR and may stabilize the kinase activation loop, DEPTOR on the contrary inhibits mTOR activity, TTI1/TEL2 is a mTOR interacting protein important for mTOR stability and assembly of the mTOR complex and maintain their activities (28) (Figure 1)
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The closest animal work involved a laminectomy (removing a small piece of the vertebra)
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