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Research Context Dihexa has been examined in the following areas: Angiotensin IV analogue design and structure–activity relationships Peptidomimetic chemistry and metabolic stabilisation of peptide-derived compounds Hepatocyte growth factor and c-Met pathway research PI3K/AKT signalling in neuronal models Dendritic spine formation and synaptogenesis in cell culture Rodent models of cognitive impairment, including transgenic Alzheimer's models Neuroinflammation markers and glial activation in animal models Blood-brain barrier permeability and oral absorption of modified peptide analogues Analytical characterisation and solubility behaviour of lipophilic research compounds The existence of published research does not establish that Dihexa is safe or effective for use in humans, and part of that published record has been formally corrected