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While synucleinopathies are all known to be multifactorial neurodegenerative diseases, it is possible that some of the factors currently recognised as contributing to disease development and progression might be rooted in changes in lipid metabolism or membrane lipid composition (Reviewed in ( PINK1 causes an accumulation of ceramides in the mitochondrial membrane, inhibiting β-oxidation and causing degradation of mitochondria via mitophagy (Vos et al., 2021
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The little women of Loja—growth hormone-receptor deficiency in an inbred population of southern Ecuador
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