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The companion REDEFINE 2 trial, reported by Davies and colleagues in the same journal in 2025, enrolled 1,206 participants with overweight or obesity and type 2 diabetes over 68 weeks and reported approximately 13.7% weight loss with improved glycemic endpoints
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On the other hand, BPC 157, a stable pentadecapeptide native and stable in human gastric juice, can be released into circulation as a cytoprotective mediator and sent to distant organs [3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21,22,23,24,27,28,29,30,31,32,34,37,39,40]
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