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Essential questions to ask before agreeing to surgery: ● "How many patients with alopecia areata have you treated surgically, and what were their outcomes?" ● "What are your exact criteria for disease stability or remission before surgery?" ● "What is your plan if my disease relapses and transplanted hair is lost?" ● "What complications should I be aware of, including poor growth, scarring, and shock loss?" If the answers feel vague, dismissive, or unrealistically optimistic, ask for written information and then seek a second opinion from an independent dermatologist or hair transplant surgeon who is not financially tied to that clinic

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For example, estrogen can reduce the production of inflammatory molecules such as cytokines (e.g., IL-1β, IL-6, and TNF-α)