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The injectable form commonly used today is essentially based on extrapolation from animal data and the hypothesis that better bioavailability equals better results

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Non-segmental vitiligo is more common, bilateral, and usually considered to be of autoimmune etiology, whereas segmental vitiligo is uncommon, present on one side of the body, and the proposed mechanism for this type is that the nerve endings of the affected region produce certain chemicals that damage the melanocytes, thereby decreasing melanin production [3]