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Research has also examined the compoundβs stability and formulation requirements
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5-amino-1MQ, an analogue from our initial series of NNMT inhibitors with low IC50 value (IC50=Λ1 ΞΌM), and high cell membrane permeability (Table 5), produced the greatest reduction of intracellular 1-MNA levels at a concentration of 10 ΞΌM among tested inhibitors
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