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The mobile phase consisted of solvent A (0.1% formic acid-acetonitrile/water (3:2 v/v)) and solvent B (0.1% formic acid-isopropanol/acetonitrile (9:1 v/v)) with a gradient elution (0–1.5 min, 68–68% A
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As a major regulator of the mtDNA transcriptional machinery, TFAM directly promotes transcription utilizing the mitochondrial RNA polymerase (92)
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